Circulating Microvesicles in Regenerative Angiogenesis
نویسندگان
چکیده
منابع مشابه
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets.
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown. In the plasma portion of blood, we found TF to be mainly associated with circulating microvesicles. By cell sorting with the specific marker CD42b, pla...
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Thrombus lysis is the consequence of a restricted number of reactions localized on the surface of fibrin and cell membranes. A functional defect or an insufficient fibrinolytic response may lead to thrombosis with severe or fatal clinical consequences. Despite this clinical need, and real progress in the knowledge of the different components of this system (plasminogen activators, inhibitors an...
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OBJECTIVE Therapeutic angiogenesis using autologous stem/progenitor cells represents a novel strategy for severe ischemic diseases. Recent reports indicated that adipose tissues could supply adipose-derived regenerative cells (ADRCs). Accordingly, we examined whether implantation of ADRCs would augment ischemia-induced angiogenesis. METHOD AND RESULTS Adipose tissue was obtained from C57BL/6J...
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ژورنال
عنوان ژورنال: Current Trends in Biomedical Engineering & Biosciences
سال: 2017
ISSN: 2572-1151
DOI: 10.19080/ctbeb.2017.03.555602